Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. Department of Neurology, The Second Hospital of Harbin, Harbin, China. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China. Department of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University, Harbin, China. Department of Statistics, Rice University, Houston, TX, USA. Department of Oncology, The First Hospital of Harbin, Harbin, China. Department of Human Genetics, University of California at Los Angeles, Los Angeles, CA, USA. Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. wangrz@126.com. School of Life Science and Technology, Harbin Institute of Technology, Harbin, 150001, China. qhjiang@hit.edu.cn. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China. liuguiyou1981@163.com.